Missouri State defeated Florida International 28-21 in Week 10, covering the 3-point spread in a competitive matchup. The Bears scored consistently throughout the game, posting seven points in each quarter for a balanced offensive attack. The Panthers matched that scoring pace through the first half with touchdowns in the first and second quarters but managed only seven points in the final two quarters combined.

The game featured eight lead changes and remained tightly contested, with Missouri State's defense making crucial plays. A notable 41-yard touchdown rush by S. Lawrence in the second quarter proved pivotal for the Bears. Florida International's Joe Pesansky led passing with 72 yards, while Kejon Owens rushed for 63 yards and Dallas Payne caught eight passes for the visitors.

The contest fell under the 50-point over-under line. Missouri State's defense generated key stops, including a significant sack-fumble of K. Jenkins in the first quarter that set the tone early. Despite Florida International's defensive efforts, the Bears' steady scoring approach proved sufficient to secure the victory on the road.