Missouri overwhelmed Massachusetts 42-6 on Saturday in a lopsided Week 5 matchup. The Tigers jumped out to an early lead with 14 first-quarter points and never looked back, adding 7 points in the second quarter, 14 in the third, and 7 in the fourth to cruise to the 36-point victory.

Massachusetts managed only a first-quarter field goal and was unable to mount any offensive momentum throughout the game. AJ Hairston led the Minutemen's passing attack with 75 yards, while Owen Anderson caught 9 passes. Despite the offensive struggles, Massachusetts' defense generated several key plays, including an interception by Timmy Hinspeter that he returned 63 yards early in the contest.

For Missouri, Marquise Davis led the ground game with 77 rushing yards. Quarterback Beau Pribula had a mixed performance, throwing a touchdown pass to Marquis Johnson but also suffering an interception and a sack for 10 yards. The Tigers' balanced attack and dominant defense controlled the game from start to finish, with the Minutemen unable to sustain any meaningful drives.